GON4L

GON-4-like protein is a protein that in humans is encoded by the GON4L gene.^[5][6] It is a nuclear protein containing two serine phosphosites and a lysine-glutamine cross-link ^[7] and is thought to be a transcription factor.^[8]

GON4L
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1UG2
Identifiers
Aliases	GON4L, GON-4, GON4, YARP, gon-4 like
External IDs	OMIM: 610393; MGI: 1917579; HomoloGene: 13002; GeneCards: GON4L; OMA:GON4L - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q22 Start 155,749,659 bp[1] End 155,859,400 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3|3 F1 Start 88,835,231 bp[2] End 88,910,103 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sural nerve granulocyte epithelium of colon buccal mucosa cell Achilles tendon right uterine tube apex of heart anterior pituitary gastric mucosa right lobe of thyroid gland Top expressed in saccule zygote otic vesicle primary oocyte otic placode spermatocyte secondary oocyte neural layer of retina tail of embryo ventricular zone More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA binding transcription corepressor activity DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component nucleoplasm nuclear body nucleus Biological process transcription, DNA-templated regulation of transcription, DNA-templated B cell differentiation negative regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 54856 76022 Ensembl ENSG00000116580 ENSMUSG00000054199 UniProt Q3T8J9 Q9DB00 RefSeq (mRNA) NM_001037533 NM_001282856 NM_001282858 NM_001282860 NM_001282861 NM_032292 NM_025174 NM_001242372 NM_027389 RefSeq (protein) NP_001269785 NP_001269787 NP_001269789 NP_001269790 NP_115668 NP_001229301 NP_081665 Location (UCSC) Chr 1: 155.75 – 155.86 Mb Chr 3: 88.84 – 88.91 Mb PubMed search [3] [4]
Wikidata
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