GPHA2

Glycoprotein hormone alpha-2 is a protein that in humans is encoded by the GPHA2 gene.^[5][6]

GPHA2
Identifiers
Aliases	GPHA2, A2, GPA2, ZSIG51, glycoprotein hormone alpha 2, glycoprotein hormone subunit alpha 2
External IDs	OMIM: 609651; MGI: 2156541; HomoloGene: 15605; GeneCards: GPHA2; OMA:GPHA2 - orthologs
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q13.1 Start 64,934,471 bp[1] End 64,935,893 bp[1]
Gene location (Mouse) Chr. Chromosome 19 (mouse)[2] Band 19|19 A Start 6,276,410 bp[2] End 6,277,798 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in oocyte body of pancreas gonad gallbladder secondary oocyte testicle right testis pituitary gland left testis anterior pituitary Top expressed in adrenal gland morula blastocyst embryo zone of skin embryo lip urinary bladder ovary testicle More reference expression data BioGPS n/a
Gene ontology Molecular function hormone activity thyrotropin-releasing hormone receptor binding protein heterodimerization activity protein binding hormone receptor binding Cellular component extracellular region intracellular anatomical structure extracellular space Biological process cell surface receptor signaling pathway regulation of signaling receptor activity G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 170589 170458 Ensembl ENSG00000149735 ENSMUSG00000024784 UniProt Q96T91 Q925Q5 RefSeq (mRNA) NM_130769 NM_130453 RefSeq (protein) NP_570125 NP_569720 Location (UCSC) Chr 11: 64.93 – 64.94 Mb Chr 19: 6.28 – 6.28 Mb PubMed search [3] [4]
Wikidata
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GPHA2 is a cystine knot-forming polypeptide and a subunit of the dimeric glycoprotein hormone family (Hsu et al., 2002). (Supplied by OMIM.)^[6]