GPHB5

Glycoprotein hormone beta-5 is a protein that in humans is encoded by the GPHB5 gene.^[5]

GPHB5
Identifiers
Aliases	GPHB5, B5, GPB5, ZLUT1, glycoprotein hormone beta 5, glycoprotein hormone subunit beta 5
External IDs	OMIM: 609652; MGI: 2156540; HomoloGene: 18476; GeneCards: GPHB5; OMA:GPHB5 - orthologs
Gene location (Human) Chr. Chromosome 14 (human)[1] Band 14q23.2 Start 63,312,835 bp[1] End 63,318,935 bp[1]
Gene location (Mouse) Chr. Chromosome 12 (mouse)[2] Band 12|12 C3 Start 75,458,496 bp[2] End 75,463,555 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gonad right hemisphere of cerebellum thigh muscle of thigh prefrontal cortex Brodmann area 9 lymph node hypothalamus right frontal lobe nucleus accumbens Top expressed in embryo primary oocyte zygote neural tube More reference expression data BioGPS n/a
Gene ontology Molecular function hormone activity thyrotropin-releasing hormone receptor binding protein heterodimerization activity protein binding Cellular component extracellular region extracellular space cytoplasm Biological process regulation of thyroid hormone mediated signaling pathway cell-cell signaling hormone-mediated signaling pathway cell surface receptor signaling pathway regulation of signaling receptor activity G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 122876 217674 Ensembl ENSG00000179600 ENSMUSG00000048982 UniProt Q86YW7 Q812B2 RefSeq (mRNA) NM_145171 NM_175644 RefSeq (protein) NP_660154 NP_783575 Location (UCSC) Chr 14: 63.31 – 63.32 Mb Chr 12: 75.46 – 75.46 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

GPHB5 is a cystine knot-forming polypeptide and a subunit of the dimeric glycoprotein hormone family (Hsu et al., 2002).[supplied by OMIM]^[5]