Top Qs
Timeline
Chat
Perspective

GPR139

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

GPR139
Remove ads

G-protein coupled receptor 139 (GPC139) is a protein that in humans is encoded by the GPR139 gene.[5][6] Research has shown that mice with loss of GCP139 experience schizophrenia-like symptomatology that is rescued with the dopamine receptor antagonist haloperidol and the μ-opioid receptor antagonist naltrexone.[7][8]

Quick Facts Identifiers, Aliases ...

In 2025, GPR139 was identified as a novel opioid receptor, specifically of dynorphins.[9]

Remove ads

Ligands

Agonists

Antagonists

References

Further reading

Loading related searches...

Wikiwand - on

Seamless Wikipedia browsing. On steroids.

Remove ads