GPR52

Probable G-protein coupled receptor 52 is a protein that in humans is encoded by the GPR52 gene.^[5][6]

GPR52
Identifiers
Aliases	GPR52, G protein-coupled receptor 52
External IDs	OMIM: 604106; MGI: 3643278; HomoloGene: 74561; GeneCards: GPR52; OMA:GPR52 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q25.1 Start 174,447,964 bp[1] End 174,449,545 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1|1 H2.1 Start 160,403,908 bp[2] End 160,405,544 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle bone marrow cells nucleus accumbens prefrontal cortex putamen caudate nucleus epithelium of colon Achilles tendon gonad Brodmann area 9 Top expressed in striatum of neuraxis superior frontal gyrus embryo primary visual cortex Hypothalamus dentate gyrus of hippocampal formation granule cell hippocampus proper duodenum granulocyte ileum More reference expression data BioGPS More reference expression data
Gene ontology Molecular function dopamine neurotransmitter receptor activity, coupled via Gs signal transducer activity G protein-coupled receptor activity G protein-coupled photoreceptor activity Cellular component integral component of membrane plasma membrane integral component of plasma membrane membrane Biological process G protein-coupled receptor signaling pathway signal transduction dopamine receptor signaling pathway locomotory behavior phototransduction detection of visible light cellular response to light stimulus Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9293 620246 Ensembl ENSG00000203737 ENSMUSG00000118401 UniProt Q9Y2T5 P0C5J4 RefSeq (mRNA) NM_005684 NM_001146330 NM_001368668 RefSeq (protein) NP_005675 NP_001139802 NP_001355597 Location (UCSC) Chr 1: 174.45 – 174.45 Mb Chr 1: 160.4 – 160.41 Mb PubMed search [3] [4]
Wikidata
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Members of the G protein-coupled receptor (GPR) family play important roles in signal transduction from the external environment to the inside of the cell.[supplied by OMIM]^[6]

Cannabidiol, CBD, and O-1918 are Inverse agonist at GPR52.^[7]