GPR68

Ovarian cancer G-protein coupled receptor 1 is a protein that in humans is encoded by the GPR68 gene.^[5][6]

GPR68
Identifiers
Aliases	GPR68, GPR12A, OGR1, G protein-coupled receptor 68, AI2A6
External IDs	OMIM: 601404; MGI: 2441763; HomoloGene: 2603; GeneCards: GPR68; OMA:GPR68 - orthologs
Gene location (Human) Chr. Chromosome 14 (human)[1] Band 14q32.11 Start 91,232,532 bp[1] End 91,253,925 bp[1]
Gene location (Mouse) Chr. Chromosome 12 (mouse)[2] Band 12|12 E Start 100,842,941 bp[2] End 100,874,457 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in tendon of biceps brachii granulocyte gingival epithelium testicle cardia pylorus buccal mucosa cell saphenous vein pituitary gland human penis Top expressed in zygote oocyte primary oocyte secondary oocyte mesenteric lymph nodes lumbar subsegment of spinal cord dentate gyrus of hippocampal formation granule cell cerebellar cortex hippocampus proper ciliary body More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane integral component of plasma membrane membrane Biological process G protein-coupled receptor signaling pathway negative regulation of monocyte differentiation positive regulation of insulin secretion involved in cellular response to glucose stimulus cellular response to pH inflammatory response positive regulation of osteoclast development signal transduction positive regulation of insulin secretion Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 8111 238377 Ensembl ENSG00000119714 ENSMUSG00000047415 UniProt Q15743 Q8BFQ3 RefSeq (mRNA) NM_001177676 NM_003485 NM_001348437 NM_001177673 NM_001177674 NM_175493 RefSeq (protein) NP_001171147 NP_003476 NP_001335366 NP_001171144 NP_001171145 NP_780702 NP_001390243 Location (UCSC) Chr 14: 91.23 – 91.25 Mb Chr 12: 100.84 – 100.87 Mb PubMed search [3] [4]
Wikidata
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See also

• Proton-sensing G protein-coupled receptors