GPR88

Probable G-protein coupled receptor 88 is a protein that in humans is encoded by the GPR88 gene.^{[5][6][7][8][9]}

GPR88
Identifiers
Aliases	GPR88, STRG, COCPMR, G protein-coupled receptor 88
External IDs	OMIM: 607468; MGI: 1927653; HomoloGene: 11104; GeneCards: GPR88; OMA:GPR88 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p21.2 Start 100,538,139 bp[1] End 100,542,021 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3|3 G1 Start 116,043,303 bp[2] End 116,047,152 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in external globus pallidus putamen caudate nucleus nucleus accumbens endothelial cell entorhinal cortex middle temporal gyrus prefrontal cortex right lobe of liver dorsolateral prefrontal cortex Top expressed in olfactory tubercle globus pallidus nucleus accumbens superior frontal gyrus lateral septal nucleus piriform cortex lumbar subsegment of spinal cord temporal lobe barrel cortex primary visual cortex More reference expression data BioGPS More reference expression data
Gene ontology Molecular function signal transducer activity cytoskeletal motor activity G protein-coupled receptor activity G protein-coupled photoreceptor activity Cellular component integral component of membrane membrane nucleus cytoplasm plasma membrane cellular component integral component of plasma membrane cilium Biological process locomotory behavior neuromuscular process controlling balance neuronal action potential signal transduction motor learning G protein-coupled receptor signaling pathway neuropeptide signaling pathway chemical synaptic transmission feeding behavior phototransduction detection of visible light cellular response to light stimulus Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 54112 64378 Ensembl ENSG00000181656 ENSMUSG00000068696 UniProt Q9GZN0 Q9EPB7 RefSeq (mRNA) NM_022049 NM_022427 RefSeq (protein) NP_071332 NP_071872 Location (UCSC) Chr 1: 100.54 – 100.54 Mb Chr 3: 116.04 – 116.05 Mb PubMed search [3] [4]
Wikidata
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Ligands

Agonists

• RTI-122^[10]