GPRC5C

G-protein coupled receptor family C group 5 member C is a protein that in humans is encoded by the GPRC5C gene.^[5][6]

GPRC5C
Identifiers
Aliases	GPRC5C, RAIG-3, RAIG3, G protein-coupled receptor class C group 5 member C
External IDs	OMIM: 605949; MGI: 1917605; HomoloGene: 11099; GeneCards: GPRC5C; OMA:GPRC5C - orthologs
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17q25.1 Start 74,424,851 bp[1] End 74,451,653 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11|11 E2 Start 114,741,978 bp[2] End 114,763,443 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right lobe of liver olfactory zone of nasal mucosa mucosa of transverse colon right lobe of thyroid gland cerebellar hemisphere left lobe of thyroid gland right hemisphere of cerebellum body of pancreas body of stomach popliteal artery Top expressed in lumbar spinal ganglion right kidney genital tubercle tail of embryo proximal tubule inner renal medulla zygote yolk sac muscle of thigh human kidney More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity signal transducer activity protein kinase activator activity Cellular component integral component of membrane vesicle receptor complex plasma membrane integral component of plasma membrane extracellular exosome cytoplasmic vesicle membrane membrane cytoplasmic vesicle intracellular membrane-bounded organelle Biological process G protein-coupled receptor signaling pathway signal transduction activation of protein kinase activity Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55890 70355 Ensembl ENSG00000170412 ENSMUSG00000051043 UniProt Q9NQ84 Q8K3J9 RefSeq (mRNA) NM_018653 NM_022036 NM_001366261 NM_001366262 NM_001110337 NM_001110338 NM_147217 RefSeq (protein) NP_061123 NP_071319 NP_001353190 NP_001353191 NP_001103807 NP_001103808 NP_671750 Location (UCSC) Chr 17: 74.42 – 74.45 Mb Chr 11: 114.74 – 114.76 Mb PubMed search [3] [4]
Wikidata
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Function

The protein encoded by this gene is a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The specific function of this protein is unknown; however, this protein may mediate the cellular effects of retinoic acid on the G protein signal transduction cascade. Two transcript variants encoding different isoforms have been found for this gene.^[6]

See also

• Retinoic acid-inducible orphan G protein-coupled receptor