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GRAM domain-containing 2B
Protein encoded by the GRAMD2B gene From Wikipedia, the free encyclopedia
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GRAM domain-containing 2B protein (GRAMD2B; formerly GRAMD3), also known as NS3TP2 and HCV NS3-transactivated protein 2 is a protein encoded by the GRAMD2B gene.[5][6]
GRAMD2B has four paralogs: GRAMD1A, GRAMD1B, GRAMD1C and GRAMD2A. These proteins are mammalian representatives of the yeast lipid transfer proteins anchored at a membrane contact site (LAM) family.[7]
GRAMD2B consists of a GRAM domain and a transmembrane domain anchoring it to the endoplasmic reticulum.[8][7] Similar to GRAMD2A, GRAMD2B lacks the VASt domain found in LAM and GRAMD1 proteins. Its function has not yet been defined, but is likely similar to that of GRAMD2A.
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