GUCY1A2

Guanylate cyclase soluble subunit alpha-2 is an enzyme that in humans is encoded by the GUCY1A2 gene.^[5][6]

GUCY1A2
Identifiers
Aliases	GUCY1A2, GC-SA2, GUC1A2, guanylate cyclase 1, soluble, alpha 2, guanylate cyclase 1 soluble subunit alpha 2
External IDs	OMIM: 601244; MGI: 2660877; HomoloGene: 47953; GeneCards: GUCY1A2; OMA:GUCY1A2 - orthologs
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q22.3 Start 106,674,019 bp[1] End 107,018,476 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 A1 Start 3,532,778 bp[2] End 3,894,736 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Brodmann area 23 lateral nuclear group of thalamus visceral pleura saphenous vein postcentral gyrus tail of epididymis lower lobe of lung external globus pallidus vena cava endothelial cell Top expressed in tail of embryo genital tubercle primary visual cortex dentate gyrus of hippocampal formation granule cell superior frontal gyrus ventricular zone embryo cerebellar cortex spermatid yolk sac More reference expression data BioGPS More reference expression data
Gene ontology Molecular function GTP binding heme binding nucleotide binding phosphorus-oxygen lyase activity lyase activity protein binding guanylate cyclase activity adenylate cyclase activity Cellular component plasma membrane guanylate cyclase complex, soluble cytoplasm Biological process signal transduction intracellular signal transduction cyclic nucleotide biosynthetic process cGMP biosynthetic process positive regulation of nitric oxide mediated signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 2977 234889 Ensembl ENSG00000152402 ENSMUSG00000041624 UniProt P33402 n/a RefSeq (mRNA) NM_001256424 NM_000855 NM_001033322 RefSeq (protein) NP_000846 NP_001243353 n/a Location (UCSC) Chr 11: 106.67 – 107.02 Mb Chr 9: 3.53 – 3.89 Mb PubMed search [3] [4]
Wikidata
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