GZMH

Granzyme H is a protein that in humans is encoded by the GZMH gene.^[5][6]

GZMH
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3TJU, 3TJV, 3TK9, 4GAW
Identifiers
Aliases	GZMH, CCP-X, CGL-2, CSP-C, CTLA1, CTSGL2, granzyme H
External IDs	OMIM: 116831; MGI: 109254; HomoloGene: 133275; GeneCards: GZMH; OMA:GZMH - orthologs
Gene location (Human) Chr. Chromosome 14 (human)[1] Band 14q12 Start 24,606,480 bp[1] End 24,609,699 bp[1]
Gene location (Mouse) Chr. Chromosome 14 (mouse)[2] Band 14 C3|14 28.19 cM Start 56,442,720 bp[2] End 56,448,874 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in granulocyte blood spleen bone marrow cells periodontal fiber decidua gallbladder lymph node right lung palpebral conjunctiva Top expressed in gastrula decidua ankle joint central gray substance of midbrain nucleus of stria terminalis uterus yolk sac tail of embryo adipose tissue dentate gyrus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function peptidase activity serine-type peptidase activity serine-type endopeptidase activity hydrolase activity Cellular component membrane secretory granule cytoplasm Biological process cytolysis apoptotic process proteolysis granzyme-mediated apoptotic signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 2999 14943 Ensembl ENSG00000100450 ENSMUSG00000015441 UniProt P20718 P08883 RefSeq (mRNA) NM_001270780 NM_001270781 NM_033423 NM_010374 RefSeq (protein) NP_001257709 NP_001257710 NP_219491 NP_034504 Location (UCSC) Chr 14: 24.61 – 24.61 Mb Chr 14: 56.44 – 56.45 Mb PubMed search [3] [4]
Wikidata
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