Glycolipid transfer protein

Glycolipid transfer protein is a cytosolic protein that catalyses the transfer of glycolipids between different intracellular membranes.^[1][2]

Glycolipid transfer protein (GLTP)
Identifiers
Symbol	GLTP
Pfam	PF08718
InterPro	IPR014830
OPM superfamily	84
OPM protein	1swx
Available protein structures: Pfam   structures / ECOD   PDB RCSB PDB; PDBe; PDBj PDBsum structure summary

It was discovered by Raymond J. Metz and Norman S. Radin in 1980 and partially purified and characterized in 1982.^[3][4]

Recent reviews on structure and possible function are available.^[5][6]

This protein transports primarily different glycosphingolipids and glyceroglycolipids between intracellular membranes, but not phospholipids. It might be also involved in translocation of glucosylceramides. It was found in brain, kidney, spleen, lung, cerebellum, liver and heart.

Human proteins containing this domain

GLTP; PLEKHA8; PLEKHA9;