Gtp binding protein 2

GTP binding protein 2 is a protein that in humans is encoded by the GTPBP2 gene. ^[5]

GTPBP2
Identifiers
Aliases	GTPBP2, GTP binding protein 2
External IDs	OMIM: 607434; MGI: 1860138; HomoloGene: 10420; GeneCards: GTPBP2; OMA:GTPBP2 - orthologs
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6p21.1 Start 43,605,316 bp[1] End 43,629,162 bp[1]
Gene location (Mouse) Chr. Chromosome 17 (mouse)[2] Band 17|17 C Start 46,471,958 bp[2] End 46,480,296 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right lobe of thyroid gland left lobe of thyroid gland mucosa of transverse colon minor salivary glands anterior pituitary upper lobe of left lung granulocyte right lung gastric mucosa monocyte Top expressed in neural layer of retina granulocyte motor neuron lip Rostral migratory stream Paneth cell pyloric antrum ciliary body fossa superior frontal gyrus More reference expression data BioGPS n/a
Gene ontology Molecular function nucleotide binding GTP binding protein binding GTPase activity translation elongation factor activity Cellular component intracellular membrane-bounded organelle extracellular region platelet alpha granule lumen Biological process platelet degranulation biological process translational elongation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 54676 56055 Ensembl ENSG00000172432 ENSMUSG00000023952 UniProt Q9BX10 Q3UJK4 RefSeq (mRNA) NM_019096 NM_001286216 NM_001145979 NM_019581 NM_001357745 RefSeq (protein) NP_001273145 NP_061969 NP_061969.3 NP_001139451 NP_062527 NP_001344674 Location (UCSC) Chr 6: 43.61 – 43.63 Mb Chr 17: 46.47 – 46.48 Mb PubMed search [3] [4]
Wikidata
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Function

GTP-binding proteins, or G proteins, constitute a superfamily capable of binding GTP or GDP. G proteins are activated by binding GTP and are inactivated by hydrolyzing GTP to GDP. This general mechanism enables G proteins to perform a wide range of biologic activities.