HECTD4

HECT domain E3 ubiquitin protein ligase 4 is a protein that in humans is encoded by the HECTD4 gene. ^[5]

HECTD4
Identifiers
Aliases	HECTD4, C12orf51, POTAGE, HECT domain E3 ubiquitin protein ligase 4, HEEL, C12ord51
External IDs	MGI: 3647820; HomoloGene: 28297; GeneCards: HECTD4; OMA:HECTD4 - orthologs
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12q24.13 Start 112,160,188 bp[1] End 112,382,439 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5|5 F Start 121,358,282 bp[2] End 121,506,640 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right hemisphere of cerebellum middle temporal gyrus ganglionic eminence Brodmann area 23 paraflocculus of cerebellum cerebellar vermis right frontal lobe primary visual cortex Brodmann area 9 prefrontal cortex Top expressed in superior cervical ganglion medial dorsal nucleus visual cortex subiculum piriform cortex central gray substance of midbrain medial geniculate nucleus primary visual cortex superior colliculus inferior colliculi More reference expression data BioGPS n/a
Gene ontology Molecular function transferase activity ubiquitin-protein transferase activity ubiquitin protein ligase activity Cellular component integral component of membrane membrane cytoplasm Biological process protein ubiquitination glucose homeostasis glucose metabolic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 283450 269700 Ensembl ENSG00000173064 ENSMUSG00000042744 UniProt Q9Y4D8 n/a RefSeq (mRNA) NM_173813 NM_001109662 NM_001388303 NM_181421 RefSeq (protein) NP_001103132 n/a Location (UCSC) Chr 12: 112.16 – 112.38 Mb Chr 5: 121.36 – 121.51 Mb PubMed search [3] [4]
Wikidata
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