HIST2H2AC

Histone H2A type 2-C is a protein that in humans is encoded by the HIST2H2AC gene.^[5][6][7][8]

H2AC20
Identifiers
Aliases	H2AC20, H2A, H2A-GL101, H2A/q, H2AFQ, histone cluster 2, H2ac, histone cluster 2 H2A family member c, H2A clustered histone 20, HIST2H2AC
External IDs	OMIM: 602797; MGI: 2448316; HomoloGene: 128596; GeneCards: H2AC20; OMA:H2AC20 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q21.2 Start 149,886,918 bp[1] End 149,887,411 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3|3 F2.1 Start 96,127,677 bp[2] End 96,128,196 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon bone marrow cells epithelium of colon corpus callosum sural nerve testicle gonad blood tonsil cervix Top expressed in uterus genital tubercle spermatocyte embryo embryo tail of embryo mesencephalon yolk sac bone marrow muscle of thigh More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein heterodimerization activity DNA binding molecular function Cellular component nucleosome nucleus chromosome extracellular exosome Biological process chromatin organization biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 8338 319176 Ensembl ENSG00000184260 ENSMUSG00000068855 UniProt Q16777 Q64523 RefSeq (mRNA) NM_003517 NM_175662 RefSeq (protein) NP_003508 NP_783593 Location (UCSC) Chr 1: 149.89 – 149.89 Mb Chr 3: 96.13 – 96.13 Mb PubMed search [3] [4]
Wikidata
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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family.^[8]