HMGN4

High mobility group nucleosome-binding domain-containing protein 4 is a transcription factor that in humans is encoded by the HMGN4 gene.^[3][4]

HMGN4
Identifiers
Aliases	HMGN4, HMG17L3, NHC, high mobility group nucleosomal binding domain 4
External IDs	HomoloGene: 105484; GeneCards: HMGN4; OMA:HMGN4 - orthologs
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6p22.2 Start 26,538,366 bp[1] End 26,546,933 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte germinal epithelium Epithelium of choroid plexus epithelium of nasopharynx parietal pleura endothelial cell granulocyte superficial temporal artery endometrium smooth muscle tissue n/a More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 10473 n/a Ensembl ENSG00000182952 n/a UniProt O00479 n/a RefSeq (mRNA) NM_006353 n/a RefSeq (protein) NP_006344 NP_006344.1 n/a Location (UCSC) Chr 6: 26.54 – 26.55 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Function

The protein encoded by this gene, a member of the HMGN protein family, is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates. Transcript variants utilizing alternative polyadenylation signals exist for this gene.^[3]

See also

• High-mobility group