HMHA1

Minor histocompatibility protein HA-1 is a protein that in humans is encoded by the HMHA1 gene.^[5][6][7]

ARHGAP45
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3D25, 3FT3
Identifiers
Aliases	ARHGAP45, HA-1, HLA-HA1, HMHA1, histocompatibility (minor) HA-1, Rho GTPase activating protein 45
External IDs	OMIM: 601155; MGI: 1917969; HomoloGene: 69120; GeneCards: ARHGAP45; OMA:ARHGAP45 - orthologs
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19p13.3 Start 1,065,923 bp[1] End 1,086,628 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10|10 C1 Start 79,852,487 bp[2] End 79,867,306 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in granulocyte blood spleen oocyte secondary oocyte monocyte lymph node thymus appendix bone marrow cells Top expressed in granulocyte thymus mesenteric lymph nodes blood spleen tibiofemoral joint bone marrow stroma of bone marrow subcutaneous adipose tissue ankle joint More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding metal ion binding GTPase activator activity Cellular component cytosol extracellular region secretory granule lumen azurophil granule lumen cytoplasm plasma membrane membrane ruffle membrane cell projection Biological process positive regulation of GTPase activity intracellular signal transduction regulation of small GTPase mediated signal transduction signal transduction neutrophil degranulation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23526 70719 Ensembl ENSG00000180448 ENSMUSG00000035697 UniProt Q92619 Q3TBD2 RefSeq (mRNA) NM_001258328 NM_001282334 NM_001282335 NM_012292 NM_001321232 NM_001142701 NM_027521 NM_001347074 RefSeq (protein) NP_001245257 NP_001269263 NP_001269264 NP_001308161 NP_036424 NP_001136173 NP_001334003 NP_081797 Location (UCSC) Chr 19: 1.07 – 1.09 Mb Chr 10: 79.85 – 79.87 Mb PubMed search [3] [4]
Wikidata
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