HSPB2

Heat shock protein beta-2 is a protein that in humans is encoded by the HSPB2 gene.^[5][6][7]

HSPB2
Identifiers
Aliases	HSPB2, HSP27, Hs.78846, LOH11CR1K, MKBP, heat shock protein family B (small) member 2
External IDs	OMIM: 602179; MGI: 1916503; HomoloGene: 68189; GeneCards: HSPB2; OMA:HSPB2 - orthologs
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q23.1 Start 111,912,734 bp[1] End 111,914,093 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9 A5.3|9 27.75 cM Start 50,662,378 bp[2] End 50,663,654 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right auricle of heart apex of heart muscle of thigh left ventricle gastrocnemius muscle Descending thoracic aorta ascending aorta popliteal artery tibial arteries gastric mucosa Top expressed in interventricular septum extraocular muscle plantaris muscle cardiac muscle tissue of left ventricle extensor digitorum longus muscle right ventricle muscle of thigh soleus muscle temporal muscle ankle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function enzyme activator activity protein binding Cellular component cytoplasm cytosol nucleus Biological process response to unfolded protein positive regulation of catalytic activity Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 3316 69253 Ensembl ENSG00000170276 ENSMUSG00000038086 UniProt Q16082 Q99PR8 RefSeq (mRNA) NM_001541 NM_001164708 NM_024441 RefSeq (protein) NP_001532 NP_001158180.1 NP_077761.3 Location (UCSC) Chr 11: 111.91 – 111.91 Mb Chr 9: 50.66 – 50.66 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Interactions

HSPB2 has been shown to interact with:

• CRYAB,^[8]
• HSPB8,^[9][10]
• Myotonic dystrophy protein kinase^[6][8] and
• TRAF6.^[11]