Top Qs
Timeline
Chat
Perspective

HTR3A

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

HTR3A
Remove ads

5-hydroxytryptamine receptor 3A is a protein that in humans is encoded by the HTR3A gene.[5][6]

Quick Facts Available structures, PDB ...
Remove ads

The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. The A subunit is the only one that can be expressed alone and forms homomers with a very low single channel conductance of 0.6pS. When combined with the B subunit and expressed as a heteromer, the single channel conductance increases immensely. Alternatively spliced transcript variants encoding different isoforms have been identified.[7]

Remove ads

See also

References

Loading content...

Further reading

Loading content...
Loading related searches...

Wikiwand - on

Seamless Wikipedia browsing. On steroids.

Remove ads