HTR3B

5-hydroxytryptamine (serotonin) receptor 3B, also known as HTR3B, is a human gene. The protein encoded by this gene is a subunit of the 5-HT3 receptor.^[5][6]

HTR3B
Identifiers
Aliases	HTR3B, 5-HT3B, 5-hydroxytryptamine receptor 3B
External IDs	OMIM: 604654; MGI: 1861899; HomoloGene: 38131; GeneCards: HTR3B; OMA:HTR3B - orthologs
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q23.2 Start 113,904,796 bp[1] End 113,949,079 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 A5.3 Start 48,846,308 bp[2] End 48,876,290 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in prefrontal cortex right frontal lobe Brodmann area 9 anterior cingulate cortex primary visual cortex superior frontal gyrus gonad kidney human kidney amygdala Top expressed in lumbar spinal ganglion female external genitalia urethra autonomic nervous system sympathetic ganglion cervical ganglion glossopharyngeal ganglion stellate ganglion embryo tunica adventitia of aorta More reference expression data BioGPS n/a
Gene ontology Molecular function extracellular ligand-gated ion channel activity ligand-gated ion channel activity serotonin-gated cation-selective channel activity ion channel activity transmembrane signaling receptor activity Cellular component integral component of membrane membrane cell surface plasma membrane postsynaptic membrane integral component of plasma membrane serotonin-activated cation-selective channel complex neuron projection synapse Biological process ion transport signal transduction ion transmembrane transport serotonin receptor signaling pathway chemical synaptic transmission regulation of membrane potential nervous system process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9177 57014 Ensembl ENSG00000149305 ENSMUSG00000008590 UniProt O95264 Q9JHJ5 RefSeq (mRNA) NM_006028 NM_001363563 NM_020274 RefSeq (protein) NP_006019 NP_001350492 NP_064670 Location (UCSC) Chr 11: 113.9 – 113.95 Mb Chr 9: 48.85 – 48.88 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse