Heat-responsive protein 12

Ribonuclease UK114 is an enzyme that in humans is encoded by the HRSP12 gene.^[5][6][7]

RIDA
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1ONI
Identifiers
Aliases	RIDA, P14.5, PSP, UK114, HRSP12, Heat-responsive protein 12, reactive intermediate imine deaminase A homolog, hp14.5
External IDs	OMIM: 602487; MGI: 1095401; HomoloGene: 4261; GeneCards: RIDA; OMA:RIDA - orthologs
Gene location (Human) Chr. Chromosome 8 (human)[1] Band 8q22.2 Start 98,102,344 bp[1] End 98,117,171 bp[1]
Gene location (Mouse) Chr. Chromosome 15 (mouse)[2] Band 15|15 B3.1 Start 34,484,167 bp[2] End 34,495,401 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right lobe of liver kidney tubule caudate nucleus nucleus accumbens putamen amygdala glomerulus human kidney anterior cingulate cortex right adrenal cortex Top expressed in right kidney human kidney left lobe of liver proximal tubule yolk sac Epithelium of choroid plexus deep cerebellar nuclei cerebellar cortex vestibular sensory epithelium vestibular membrane of cochlear duct More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein homodimerization activity ion binding long-chain fatty acid binding transition metal ion binding hydrolase activity RNA binding deaminase activity endoribonuclease activity, producing 3'-phosphomonoesters Cellular component cytosol mitochondrion extracellular exosome nucleus cytoplasm mitochondrial matrix peroxisome Biological process kidney development lung development G1 to G0 transition response to lipid brain development response to salt negative regulation of epithelial cell proliferation RNA phosphodiester bond hydrolysis, endonucleolytic organonitrogen compound catabolic process negative regulation of translation L-threonine catabolic process to glycine Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10247 15473 Ensembl ENSG00000132541 ENSMUSG00000022323 UniProt P52758 P52760 RefSeq (mRNA) NM_005836 NM_008287 RefSeq (protein) NP_005827 NP_032313 Location (UCSC) Chr 8: 98.1 – 98.12 Mb Chr 15: 34.48 – 34.5 Mb PubMed search [3] [4]
Wikidata
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