Hexestrol diphosphate

Hexestrol diphosphate (brand names Cytostatin, Cytostesin, Pharmestrin, Retalon Aquosum) is a synthetic, nonsteroidal estrogen of the stilbestrol group related to diethylstilbestrol and used as an estrogen and antineoplastic agent in the treatment of prostate cancer.^[1][2][3] It is a water-soluble ester of hexestrol.^[1] The medication has been known since at least 1956.^[3]

Hexestrol diphosphate

Clinical data
Trade names	Cytostatin, Cytostesin, Pharmestrin, Retalon Aquosum
Other names	DA-268; NSC-35752
Routes of administration	Intravenous injection
Drug class	Estrogen; Nonsteroidal estrogen
Identifiers
IUPAC name [4-[(3S,4R)-4-(4-phosphonooxyphenyl)hexan-3-yl]phenyl] dihydrogen phosphate
CAS Number	24809-02-7
PubChem CID	193055
ChemSpider	167536
UNII	30L14W008X
ChEMBL	ChEMBL1162236
CompTox Dashboard (EPA)	DTXSID901016489
Chemical and physical data
Formula	C18H24O8P2
Molar mass	430.330 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCC(C1=CC=C(C=C1)OP(=O)(O)O)C(CC)C2=CC=C(C=C2)OP(=O)(O)O
InChI InChI=1S/C18H24O8P2/c1-3-17(13-5-9-15(10-6-13)25-27(19,20)21)18(4-2)14-7-11-16(12-8-14)26-28(22,23)24/h5-12,17-18H,3-4H2,1-2H3,(H2,19,20,21)(H2,22,23,24)/t17-,18+ Key:JBDIWCWZUDNWTL-HDICACEKSA-N

See also

• Hexestrol diacetate
• Hexestrol dicaprylate
• Hexestrol dipropionate