IFIT1

Interferon-induced protein with tetratricopeptide repeats 1 is a protein that in humans is encoded by the IFIT1 gene.^[4][5][6]

IFIT1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4HOU
Identifiers
Aliases	IFIT1, C56, G10P1, IFI-56, IFI-56K, IFI56, IFIT-1, IFNAI1, ISG56, P56, RNM561, interferon induced protein with tetratricopeptide repeats 1
External IDs	OMIM: 147690; MGI: 2148249; HomoloGene: 78213; GeneCards: IFIT1; OMA:IFIT1 - orthologs
Gene location (Mouse) Chr. Chromosome 19 (mouse)[1] Band 19|19 C1 Start 34,594,449 bp[1] End 34,618,143 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in pons trigeminal ganglion biceps brachii glomerulus metanephric glomerulus palpebral conjunctiva subthalamic nucleus germinal epithelium amniotic fluid parietal pleura Top expressed in epithelium of small intestine zygote jejunum secondary oocyte ileum interventricular septum granulocyte primary oocyte duodenum migratory enteric neural crest cell More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding RNA binding Cellular component cytoplasm host cell cytosol Biological process negative regulation of helicase activity response to virus positive regulation of viral genome replication negative regulation of viral genome replication negative regulation of defense response to virus by host cellular response to type I interferon viral process intracellular transport of viral protein in host cell negative regulation of protein binding type I interferon signaling pathway innate immune response regulation of defense response to virus cellular response to exogenous dsRNA immune system process defense response to virus response to bacterium cellular response to interferon-beta Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 3434 112419 Ensembl n/a ENSMUSG00000067297 UniProt P09914 Q3U687 RefSeq (mRNA) NM_001548 NM_001270927 NM_001270928 NM_001270929 NM_001270930 NM_053217 NM_001362130 RefSeq (protein) NP_001257856 NP_001257857 NP_001257858 NP_001257859 NP_001539 NP_444447 NP_001349059 Location (UCSC) n/a Chr 19: 34.59 – 34.62 Mb PubMed search [2] [3]
Wikidata
View/Edit Human View/Edit Mouse