IFNA21

Interferon alpha-21 is a protein that in humans is encoded by the IFNA21 gene.^[5][6]

IFNA21
Identifiers
Aliases	IFNA21, IFN-alphaI, LeIF F, leIF-F, interferon, alpha 21, interferon alpha 21
External IDs	OMIM: 147584; MGI: 2667155; HomoloGene: 88661; GeneCards: IFNA21; OMA:IFNA21 - orthologs
Gene location (Human) Chr. Chromosome 9 (human)[1] Band 9p21.3 Start 21,165,637 bp[1] End 21,166,660 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band 4 C4|4 42.02 cM Start 88,561,878 bp[2] End 88,562,696 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in cerebellar hemisphere right hemisphere of cerebellum Brodmann area 9 hypothalamus Cortex of frontal lobe prefrontal cortex lymph node nucleus accumbens islet of Langerhans mesencephalon Top expressed in embryo embryo More reference expression data BioGPS More reference expression data
Gene ontology Molecular function cytokine activity type I interferon receptor binding cytokine receptor binding Cellular component extracellular region extracellular space Biological process natural killer cell activation involved in immune response B cell differentiation defense response B cell proliferation blood coagulation positive regulation of peptidyl-serine phosphorylation of STAT protein humoral immune response adaptive immune response defense response to virus type I interferon signaling pathway response to exogenous dsRNA T cell activation involved in immune response cytokine-mediated signaling pathway innate immune response regulation of signaling receptor activity Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 3452 230396 Ensembl ENSG00000137080 ENSMUSG00000063376 UniProt P01568 Q80SU4 RefSeq (mRNA) NM_002175 NM_177347 RefSeq (protein) NP_002166 NP_796321 Location (UCSC) Chr 9: 21.17 – 21.17 Mb Chr 4: 88.56 – 88.56 Mb PubMed search [3] [4]
Wikidata
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