IFT57

Intraflagellar transport protein 57 homolog is a protein that in humans is encoded by the IFT57 gene.^[5]

IFT57
Identifiers
Aliases	IFT57, ESRRBL1, HIPPI, MHS4R2, intraflagellar transport 57, OFD18
External IDs	OMIM: 606621; MGI: 1921166; HomoloGene: 32383; GeneCards: IFT57; OMA:IFT57 - orthologs
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3q13.12-q13.13 Start 108,160,812 bp[1] End 108,222,435 bp[1]
Gene location (Mouse) Chr. Chromosome 16 (mouse)[2] Band 16|16 B5 Start 49,519,596 bp[2] End 49,585,489 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in bronchial epithelial cell sperm caput epididymis left testis mucosa of paranasal sinus right testis olfactory zone of nasal mucosa epithelium of nasopharynx corpus epididymis right uterine tube Top expressed in Epithelium of choroid plexus fossa islet of Langerhans seminiferous tubule condyle ciliary body barrel cortex vestibular sensory epithelium lateral geniculate nucleus medial geniculate nucleus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA binding protein binding Cellular component intraciliary transport particle B cytoplasm ciliary basal body centrosome Golgi apparatus cell projection photoreceptor connecting cilium dendrite terminus ciliary tip axoneme cytoskeleton cilium Biological process regulation of apoptotic process regulation of transcription, DNA-templated intraciliary transport transcription, DNA-templated heart looping neural tube closure negative regulation of epithelial cell proliferation smoothened signaling pathway left/right pattern formation activation of cysteine-type endopeptidase activity involved in apoptotic process apoptotic process intraciliary transport involved in cilium assembly motile cilium assembly non-motile cilium assembly cilium assembly Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55081 73916 Ensembl ENSG00000114446 ENSMUSG00000032965 UniProt Q9NWB7 Q8BXG3 RefSeq (mRNA) NM_018010 NM_028680 RefSeq (protein) NP_060480 NP_082956 Location (UCSC) Chr 3: 108.16 – 108.22 Mb Chr 16: 49.52 – 49.59 Mb PubMed search [3] [4]
Wikidata
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Interactions

IFT57 has been shown to interact with Caspase 8.^[6]