IGFBP6

Insulin-like growth factor-binding protein 6 (IGFBP-6) is a protein that in humans is encoded by the IGFBP6 gene.^[4][5][6]

IGFBP6
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1RMJ
Identifiers
Aliases	IGFBP6, IBP6, insulin like growth factor binding protein 6
External IDs	OMIM: 146735; MGI: 96441; HomoloGene: 1641; GeneCards: IGFBP6; OMA:IGFBP6 - orthologs
Gene location (Mouse) Chr. Chromosome 15 (mouse)[1] Band 15|15 F2 Start 102,052,797 bp[1] End 102,057,946 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon tibial nerve gastric mucosa canal of the cervix left uterine tube right coronary artery thoracic aorta ascending aorta trigeminal ganglion left coronary artery Top expressed in ankle uterus right lung right lung lobe ankle joint cervix left lung lip white adipose tissue esophagus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function insulin-like growth factor binding signaling receptor binding growth factor binding insulin-like growth factor I binding insulin-like growth factor II binding fibronectin binding Cellular component cytoplasm Golgi apparatus extracellular region extracellular space insulin-like growth factor binary complex Biological process regulation of insulin-like growth factor receptor signaling pathway negative regulation of canonical Wnt signaling pathway regulation of cell growth signal transduction negative regulation of cell population proliferation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 3489 16012 Ensembl n/a ENSMUSG00000023046 UniProt P24592 P47880 RefSeq (mRNA) NM_002178 NM_008344 RefSeq (protein) NP_002169 NP_032370 Location (UCSC) n/a Chr 15: 102.05 – 102.06 Mb PubMed search [2] [3]
Wikidata
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