IL17RC

Interleukin-17 receptor C is a protein that in humans is encoded by the IL17RC gene.^[5][6]

IL17RC
Identifiers
Aliases	IL17RC, IL17-RL, IL17RL, CANDF9, interleukin 17 receptor C
External IDs	OMIM: 610925; MGI: 2159336; HomoloGene: 15894; GeneCards: IL17RC; OMA:IL17RC - orthologs
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3p25.3|3p25.3-p24.1 Start 9,917,074 bp[1] End 9,933,630 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6|6 E3 Start 113,448,388 bp[2] End 113,460,101 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in anterior pituitary right adrenal cortex right lobe of liver gastric mucosa left adrenal cortex skin of abdomen skin of leg muscle layer of sigmoid colon apex of heart right lobe of thyroid gland Top expressed in ileum jejunum lip esophagus colon zone of skin urinary bladder white adipose tissue duodenum humerus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function interleukin-17 receptor activity signaling receptor binding Cellular component integral component of membrane cell surface integral component of plasma membrane membrane plasma membrane Biological process positive regulation of cytokine production involved in inflammatory response granulocyte chemotaxis defense response to fungus interleukin-17-mediated signaling pathway cytokine-mediated signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 84818 171095 Ensembl ENSG00000163702 ENSMUSG00000030281 UniProt Q8NAC3 Q8K4C2 RefSeq (mRNA) NM_001203263 NM_001203264 NM_001203265 NM_032732 NM_153460 NM_153461 NM_153462 NM_153463 NM_001367278 NM_001367279 NM_001367280 NM_134159 NM_178942 RefSeq (protein) NP_001190192 NP_001190193 NP_001190194 NP_116121 NP_703190 NP_703191 NP_001354207 NP_001354208 NP_001354209 NP_598920 NP_849273 Location (UCSC) Chr 3: 9.92 – 9.93 Mb Chr 6: 113.45 – 113.46 Mb PubMed search [3] [4]
Wikidata
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Function

This gene encodes a single-pass transmembrane protein that shares limited similarity with the interleukin-17 receptor. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, but the full-length nature of only three have been determined to date.^[6]

See also

• Interleukin-17 receptor