IMP3

U3 small nucleolar ribonucleoprotein protein IMP3 is a protein that in humans is encoded by the IMP3 gene.^[5][6][7]

IMP3
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2CQJ
Identifiers
Aliases	IMP3, BRMS2, C15orf12, MRPS4, U3 small nucleolar ribonucleoprotein, IMP U3 small nucleolar ribonucleoprotein 3
External IDs	OMIM: 612980; MGI: 1916119; HomoloGene: 6120; GeneCards: IMP3; OMA:IMP3 - orthologs
Gene location (Human) Chr. Chromosome 15 (human)[1] Band 15q24.2 Start 75,639,085 bp[1] End 75,648,706 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 B Start 56,844,759 bp[2] End 56,845,682 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in mucosa of transverse colon granulocyte skin of abdomen right lobe of liver right adrenal gland right adrenal cortex left adrenal gland mucosa of esophagus left adrenal cortex skin of leg Top expressed in embryo embryo medial ganglionic eminence lactiferous gland choroid plexus of fourth ventricle condyle fossa lip epiblast endocardial cushion More reference expression data BioGPS More reference expression data
Gene ontology Molecular function structural constituent of ribosome rRNA binding protein binding snoRNA binding RNA binding Cellular component small ribosomal subunit small-subunit processome Mpp10 complex nucleolus intracellular anatomical structure nucleus nucleoplasm preribosome Biological process positive regulation of translational fidelity ribosome biogenesis rRNA processing Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55272 102462 Ensembl ENSG00000177971 ENSMUSG00000032288 UniProt Q9NV31 Q921Y2 RefSeq (mRNA) NM_018285 NM_133976 RefSeq (protein) NP_060755 NP_598737 Location (UCSC) Chr 15: 75.64 – 75.65 Mb Chr 9: 56.84 – 56.85 Mb PubMed search [3] [4]
Wikidata
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Function

This gene encodes the human homolog of the yeast Imp3 protein. The protein localizes to the nucleoli and interacts with the U3 snoRNP complex. The protein contains an S4 domain.^[7]