ITM2C

Integral membrane protein 2C is a protein that in humans is encoded by the ITM2C gene.^[5][6]

ITM2C
Identifiers
Aliases	ITM2C, BRI3, BRICD2C, E25, E25C, ITM3, integral membrane protein 2C
External IDs	OMIM: 609554; MGI: 1927594; HomoloGene: 11186; GeneCards: ITM2C; OMA:ITM2C - orthologs
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2q37.1 Start 230,864,639 bp[1] End 230,879,248 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1|1 C5 Start 85,822,002 bp[2] End 85,836,396 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in mucosa of transverse colon nucleus accumbens anterior cingulate cortex caudate nucleus amygdala external globus pallidus rectum prefrontal cortex hypothalamus putamen Top expressed in olfactory tubercle nucleus accumbens nucleus of stria terminalis supraoptic nucleus entorhinal cortex arcuate nucleus CA3 field lateral septal nucleus median eminence paraventricular nucleus of hypothalamus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function amyloid-beta binding protein binding ATP binding Cellular component perinuclear region of cytoplasm integral component of membrane lysosomal membrane extracellular exosome membrane lysosome plasma membrane Golgi apparatus Biological process positive regulation of extrinsic apoptotic signaling pathway negative regulation of neuron projection development neuron differentiation negative regulation of amyloid precursor protein biosynthetic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 81618 64294 Ensembl ENSG00000135916 ENSMUSG00000026223 UniProt Q9NQX7 Q91VK4 RefSeq (mRNA) NM_030926 NM_001012514 NM_001012516 NM_001287240 NM_001287241 NM_022417 RefSeq (protein) NP_001012532 NP_001012534 NP_001274169 NP_001274170 NP_112188 NP_071862 Location (UCSC) Chr 2: 230.86 – 230.88 Mb Chr 1: 85.82 – 85.84 Mb PubMed search [3] [4]
Wikidata
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