Inositol-hexakisphosphate kinase

Inositol-hexakisphosphate kinase (EC 2.7.4.21, ATP:1D-myo-inositol-hexakisphosphate phosphotransferase) is an enzyme with systematic name ATP:1D-myo-inositol-hexakisphosphate 5-phosphotransferase.^[1][2][3] This enzyme catalyses the following chemical reaction

(1) ATP + 1D-myo-inositol hexakisphosphate(Phytic acid) ${\displaystyle \rightleftharpoons }$ ADP + 1D-myo-inositol 5-diphosphate 1,2,3,4,6-pentakisphosphate

(2) ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate ${\displaystyle \rightleftharpoons }$ ADP + 1D-myo-inositol diphosphate tetrakisphosphate (isomeric configuration unknown)

Inositol-hexakisphosphate kinase
Identifiers
EC no.	2.7.4.21
CAS no.	176898-37-6
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Three mammalian isoforms are known to exist.

See also

• IHPK1
• IHPK2