Interleukin-27 receptor

The interleukin-27 receptor is a type I cytokine receptor for interleukin-27. It is a heterodimer composed of the interleukin 27 receptor, alpha subunit^[1][2] and glycoprotein 130.^[3]

interleukin 27 receptor, alpha
Identifiers
Symbol	IL27RA
Alt. symbols	WSX-1, TCCR, CRL1, WSX1, zcytor1, IL-27R
NCBI gene	9466
HGNC	17290
OMIM	605350
RefSeq	NM_004843
UniProt	Q6UWB1
Other data
Locus	Chr. 19 p13.11
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interleukin 6 signal transducer (gp130, oncostatin M receptor)
Identifiers
Symbol	IL6ST
Alt. symbols	GP130, CD130
NCBI gene	3572
HGNC	6021
OMIM	600694
RefSeq	NM_002184
UniProt	P40189
Other data
Locus	Chr. 5 q11
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IL27RA essential for transcriptional activation of STAT1 and for augmenting the induction of T-bet expression during initiation of Th1 cell differentiation.^[4]