IPALT

IPALT
Clinical data
Other names	ALiPT; ASR-3003; ASR3003; N-Isopropyl-N-allyltryptamine; N-Allyl-N-isopropyltryptamine
Drug class	Serotonin receptor modulator; Serotonin 5-HT2A receptor agonist
ATC code	None;
Identifiers
	IUPAC name N-[2-(1H-indol-3-yl)ethyl]-N-prop-2-enylpropan-2-amine;
PubChem CID	156836231;
Chemical and physical data
Formula	C16H22N2
Molar mass	242.366 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(C)N(CCC1=CNC2=CC=CC=C21)CC=C;
	InChI InChI=1S/C16H22N2/c1-4-10-18(13(2)3)11-9-14-12-17-16-8-6-5-7-15(14)16/h4-8,12-13,17H,1,9-11H2,2-3H3; Key:DYIILRIYTXJTNJ-UHFFFAOYSA-N;

iPALT, or ALiPT, also known as N-isopropyl-N-allyltryptamine or by its developmental code name ASR-3003, is a serotonin receptor modulator of the tryptamine family.^[1] It is an asymmetrical analogue of diisopropyltryptamine (DiPT) and diallyltryptamine (DALT).^[1] The drug is a non-selective serotonin receptor agonist, including of the serotonin 5-HT_1B, 5-HT_2A, 5-HT_2B, and 5-HT₆ receptors, but not of the serotonin 5-HT_1A receptor.^[1] It is also a serotonin reuptake inhibitor, but does not inhibit dopamine or norepinephrine reuptake.^[1] The drug shows rather low potency for many of these actions, with for example 47-fold lower potency as a serotonin 5-HT_2A receptor agonist than the known psychedelic drug 5-MeO-iPALT (ASR-3001).^[1] The chemical synthesis of iPALT has been described.^[1] Derivatives of iPALT include 5-MeO-iPALT (ASR-3001), 4-HO-iPALT, and 2-Me-iPALT (ASR-3002).^[1] 5-MeO-iPALT is known to be a psychedelic drug in humans and is under development for potential medical use.^[2]^[3]^[4]^[5] iPALT was patented by the Alexander Shulgin Research Institute (ASRI) in 2024.^[1]

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See also