Isothiazole

Isothiazole, or 1,2-thiazole, is an organic compound consisting with the formula (CH)₃S(N). The ring is unsaturated and features an S-N bond.^[4] The isomeric thiazole, where the S and N are not directly bonded are far more common.

Isothiazole

Names
Preferred IUPAC name 1,2-Thiazole[1]
Other names isothiazole
Identifiers
CAS Number	288-16-4 Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:35600 Y
ChemSpider	60838 Y
ECHA InfoCard	100.241.294
PubChem CID	67515
UNII	38FAO14250 Y
CompTox Dashboard (EPA)	DTXSID90182980
InChI InChI=1S/C3H3NS/c1-2-4-5-3-1/h1-3H Y Key: ZLTPDFXIESTBQG-UHFFFAOYSA-N Y InChI=1/C3H3NS/c1-2-4-5-3-1/h1-3H Key: ZLTPDFXIESTBQG-UHFFFAOYAS
SMILES n1sccc1
Properties
Chemical formula	C3H3NS
Molar mass	85.12 g·mol−1
Boiling point	114 °C (237 °F; 387 K)[2]
Acidity (pKa)	−0.5 (of conjugate acid)[3]
Related compounds
Related compounds	thiazole, isoxazole
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Y verify (what is YN ?) Infobox references

Isothiazones are produced by oxidation of enamine-thiones.^[5] The ring structure of isothiazole is incorporated into larger compounds with biological activity such as the pharmaceutical drugs ziprasidone and perospirone.

See also

• Isothiazolinone