Itruvone

Itruvone
Clinical data
Other names	PH10; PH10A; PH10 NS; Pregn-4-en-20-yn-3-one
Routes of; administration	Intranasal (spray)
Identifiers
	IUPAC name (8S,9S,10R,13S,14S,17R)-17-ethynyl-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one;
CAS Number	21321-89-1;
PubChem CID	15633961;
ChemSpider	18829396;
UNII	72HML2UK6J;
KEGG	D12542;
Chemical and physical data
Formula	C21H28O
Molar mass	296.454 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2C#C)CCC4=CC(=O)CC[C@]34C;
	InChI InChI=1S/C21H28O/c1-4-14-6-8-18-17-7-5-15-13-16(22)9-11-21(15,3)19(17)10-12-20(14,18)2/h1,13-14,17-19H,5-12H2,2-3H3/t14-,17-,18-,19-,20+,21-/m0/s1; Key:CHOUAXDNNAVGHR-NWSAAYAGSA-N;

Itruvone (INNTooltip International Nonproprietary Name; developmental code name PH10), also known as pregn-4-en-20-yn-3-one, is a vomeropherine which is under development by VistaGen Therapeutics as a nasal spray for the treatment of major depressive disorder.^[1]^[2]^[3]^[4]^[5]^[6]

Quick facts Clinical data, Other names ...

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Itruvone

See also

References

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