JAKMIP2

Janus kinase and microtubule interacting protein 2 is a protein that in humans is encoded by the JAKMIP2 gene. ^[5]

JAKMIP2
Identifiers
Aliases	JAKMIP2, JAMIP2, NECC1, janus kinase and microtubule interacting protein 2
External IDs	OMIM: 611197; MGI: 1923467; HomoloGene: 8866; GeneCards: JAKMIP2; OMA:JAKMIP2 - orthologs
Gene location (Human) Chr. Chromosome 5 (human)[1] Band 5q32 Start 147,585,438 bp[1] End 147,782,775 bp[1]
Gene location (Mouse) Chr. Chromosome 18 (mouse)[2] Band 18|18 B3 Start 43,664,472 bp[2] End 43,820,838 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ventricular zone sural nerve middle temporal gyrus ganglionic eminence corpus callosum dorsal motor nucleus of vagus nerve entorhinal cortex prefrontal cortex postcentral gyrus Brodmann area 46 Top expressed in habenula piriform cortex lobe of cerebellum mammillary body anterior amygdaloid area ventromedial nucleus subiculum cerebellar vermis lateral hypothalamus primary motor cortex More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 9832 76217 Ensembl ENSG00000176049 ENSMUSG00000024502 UniProt Q96AA8 D3YXK0 RefSeq (mRNA) NM_014790 NM_001270934 NM_001270941 NM_001282282 NM_001163637 RefSeq (protein) NP_001257863 NP_001257870 NP_001269211 NP_055605 NP_001157109 Location (UCSC) Chr 5: 147.59 – 147.78 Mb Chr 18: 43.66 – 43.82 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Function

The protein encoded by this gene is reported to be a component of the Golgi matrix. It may act as a golgin protein by negatively regulating transit of secretory cargo and by acting as a structural scaffold of the Golgi. Alternative splicing results in multiple transcript variants.