KCNB2

Potassium voltage-gated channel subfamily B member 2 is a protein that in humans is encoded by the KCNB2 gene.^[5][6] The protein encoded by this gene is a voltage-gated potassium channel subunit.^[5][6]

KCNB2
Identifiers
Aliases	KCNB2, KV2.2, potassium voltage-gated channel subfamily B member 2
External IDs	OMIM: 607738; MGI: 99632; HomoloGene: 31263; GeneCards: KCNB2; OMA:KCNB2 - orthologs
Gene location (Human) Chr. Chromosome 8 (human)[1] Band 8q21.11 Start 72,537,225 bp[1] End 72,938,349 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1 A3|1 4.5 cM Start 15,357,478 bp[2] End 15,793,974 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in buccal mucosa cell testicle islet of Langerhans ganglionic eminence prefrontal cortex Brodmann area 23 ventricular zone dorsolateral prefrontal cortex Brodmann area 9 entorhinal cortex Top expressed in olfactory bulb dentate gyrus of hippocampal formation granule cell ganglionic eminence neural tube Mesencephalon hippocampus proper ganglion of neuraxis secondary oocyte Cortex of frontal lobe primary visual cortex More reference expression data BioGPS n/a
Gene ontology Molecular function potassium channel activity delayed rectifier potassium channel activity voltage-gated ion channel activity ion channel activity protein heterodimerization activity voltage-gated potassium channel activity Cellular component perikaryon cell projection membrane voltage-gated potassium channel complex plasma membrane neuronal cell body membrane dendrite integral component of membrane soma Biological process regulation of smooth muscle contraction regulation of ion transmembrane transport ion transport potassium ion transport transmembrane transport protein homooligomerization potassium ion transmembrane transport protein localization to plasma membrane Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9312 98741 Ensembl ENSG00000182674 ENSMUSG00000092083 UniProt Q92953 A6H8H5 RefSeq (mRNA) NM_004770 NM_001033195 NM_001098528 RefSeq (protein) NP_004761 NP_001091998 Location (UCSC) Chr 8: 72.54 – 72.94 Mb Chr 1: 15.36 – 15.79 Mb PubMed search [3] [4]
Wikidata
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