KCNG1

Potassium voltage-gated channel subfamily G member 1 is a protein that in humans is encoded by the KCNG1 gene.^[5][6][7]

KCNG1
Identifiers
Aliases	KCNG1, K13, KCNG, KV6.1, kH2, potassium voltage-gated channel modifier subfamily G member 1
External IDs	OMIM: 603788; MGI: 3616086; HomoloGene: 20515; GeneCards: KCNG1; OMA:KCNG1 - orthologs
Gene location (Human) Chr. Chromosome 20 (human)[1] Band 20q13.13 Start 51,003,656 bp[1] End 51,023,107 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 H3 Start 168,102,037 bp[2] End 168,123,656 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in body of uterus ventricular zone left uterine tube ganglionic eminence stromal cell of endometrium buccal mucosa cell tail of epididymis myometrium entorhinal cortex seminal vesicula Top expressed in dentate gyrus of hippocampal formation granule cell subiculum hippocampus proper superior frontal gyrus facial motor nucleus temporal lobe amygdala visual cortex primary visual cortex prefrontal cortex More reference expression data BioGPS More reference expression data
Gene ontology Molecular function voltage-gated potassium channel activity ion channel activity potassium channel activity delayed rectifier potassium channel activity voltage-gated ion channel activity Cellular component integral component of membrane voltage-gated potassium channel complex plasma membrane membrane Biological process potassium ion transport regulation of ion transmembrane transport regulation of delayed rectifier potassium channel activity protein homooligomerization ion transport transmembrane transport potassium ion transmembrane transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 3755 241794 Ensembl ENSG00000026559 ENSMUSG00000074575 UniProt Q9UIX4 A2BDX4 RefSeq (mRNA) NM_002237 NM_172318 NM_001081134 NM_001379458 RefSeq (protein) NP_002228 NP_001074603 NP_001366387 Location (UCSC) Chr 20: 51 – 51.02 Mb Chr 2: 168.1 – 168.12 Mb PubMed search [3] [4]
Wikidata
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Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This gene is abundantly expressed in skeletal muscle. Alternative splicing results in at least two transcript variants encoding distinct isoforms.^[7]

See also

• Voltage-gated potassium channel