KCNK10

Potassium channel, subfamily K, member 10, also known as KCNK10 is a human gene. The protein encoded by this gene, K_2P10.1, is a potassium channel containing two pore-forming P domains.^[5][6][7]

KCNK10
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 4BW5, 4XDJ, 4XDK, 4XDL
Identifiers
Aliases	KCNK10, K2p10.1, PPP1R97, TREK-2, TREK2, potassium two pore domain channel subfamily K member 10
External IDs	OMIM: 605873; MGI: 1919508; HomoloGene: 11321; GeneCards: KCNK10; OMA:KCNK10 - orthologs
Gene location (Human) Chr. Chromosome 14 (human)[1] Band 14q31.3 Start 88,180,103 bp[1] End 88,326,907 bp[1]
Gene location (Mouse) Chr. Chromosome 12 (mouse)[2] Band 12|12 E Start 98,395,696 bp[2] End 98,544,569 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in cerebellar vermis pons ventricular zone Brodmann area 23 superior vestibular nucleus ventral tegmental area jejunal mucosa dorsal motor nucleus of vagus nerve parietal lobe inferior olivary nucleus Top expressed in ventricular zone spermatocyte lumbar spinal ganglion ganglionic eminence medial ganglionic eminence cerebellar cortex neural tube trigeminal ganglion mesencephalon lobe of cerebellum More reference expression data BioGPS n/a
Gene ontology Molecular function potassium channel activity voltage-gated ion channel activity potassium ion leak channel activity Cellular component integral component of membrane plasma membrane membrane integral component of plasma membrane Biological process potassium ion transport regulation of ion transmembrane transport memory ion transport signal transduction stabilization of membrane potential potassium ion transmembrane transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 54207 72258 Ensembl ENSG00000100433 ENSMUSG00000033854 UniProt P57789 n/a RefSeq (mRNA) NM_021161 NM_138317 NM_138318 NM_029911 NM_001316664 NM_001316665 NM_001316666 RefSeq (protein) NP_066984 NP_612190 NP_612191 n/a Location (UCSC) Chr 14: 88.18 – 88.33 Mb Chr 12: 98.4 – 98.54 Mb PubMed search [3] [4]
Wikidata
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See also

• Tandem pore domain potassium channel