KCNV1

Potassium voltage-gated channel subfamily V member 1 is a protein that in humans is encoded by the KCNV1 gene.^[5][6] The protein encoded by this gene is a voltage-gated potassium channel subunit.^[5][6]

KCNV1
Identifiers
Aliases	KCNV1, HNKA, KCNB3, KV2.3, KV8.1, potassium voltage-gated channel modifier subfamily V member 1
External IDs	OMIM: 608164; MGI: 1914748; HomoloGene: 22811; GeneCards: KCNV1; OMA:KCNV1 - orthologs
Gene location (Human) Chr. Chromosome 8 (human)[1] Band 8q23.2 Start 109,963,636 bp[1] End 109,975,771 bp[1]
Gene location (Mouse) Chr. Chromosome 15 (mouse)[2] Band 15|15 B3.3 Start 44,969,680 bp[2] End 44,978,316 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in buccal mucosa cell prefrontal cortex endothelial cell dorsolateral prefrontal cortex Brodmann area 9 superior frontal gyrus right frontal lobe Brodmann area 23 Brodmann area 46 cingulate gyrus Top expressed in lumbar spinal ganglion prefrontal cortex primary motor cortex superior frontal gyrus primary visual cortex piriform cortex dentate gyrus of hippocampal formation granule cell temporal lobe hippocampus proper cingulate gyrus More reference expression data BioGPS n/a
Gene ontology Molecular function ion channel inhibitor activity potassium channel regulator activity ion channel activity voltage-gated ion channel activity potassium channel activity voltage-gated potassium channel activity Cellular component plasma membrane membrane voltage-gated potassium channel complex integral component of membrane integral component of plasma membrane Biological process ion transport transmembrane transport potassium ion transport protein homooligomerization regulation of ion transmembrane transport potassium ion transmembrane transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 27012 67498 Ensembl ENSG00000164794 ENSMUSG00000022342 UniProt Q6PIU1 Q8BZN2 RefSeq (mRNA) NM_014379 NM_026200 RefSeq (protein) NP_055194 NP_080476 Location (UCSC) Chr 8: 109.96 – 109.98 Mb Chr 15: 44.97 – 44.98 Mb PubMed search [3] [4]
Wikidata
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Common variations in the KCNV1 gene have been associated with schizophrenia.^[7]