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KDM3A

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

KDM3A
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Lysine demethylase 3A is a protein that in humans is encoded by the KDM3A gene.[5]

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Function

This gene encodes a zinc finger protein that contains a jumonji C (JmjC) domain and may play a role in hormone-dependent transcriptional activation. Alternative splicing results in multiple transcript variants. KDM3A catalyzes the demethylation of H3K9me1 and H3K9me2 residues. Its function is dependent on the presence of cofactors Fe(II) and α-Ketoglutarate.[6]

References

Further reading

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