KDM3B

Lysine-specific demethylase 3B is an enzyme that in humans is encoded by the KDM3B gene.^[5][6] KDM3B belongs to the alpha-ketoglutarate-dependent hydroxylase superfamily.

KDM3B
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4C8D
Identifiers
Aliases	KDM3B, 5qNCA, C5orf7, JMJD1B, NET22, lysine demethylase 3B, DIJOS
External IDs	OMIM: 609373; MGI: 1923356; HomoloGene: 41145; GeneCards: KDM3B; OMA:KDM3B - orthologs
Gene location (Human) Chr. Chromosome 5 (human)[1] Band 5q31.2 Start 138,352,685 bp[1] End 138,437,028 bp[1]
Gene location (Mouse) Chr. Chromosome 18 (mouse)[2] Band 18|18 B1 Start 34,910,100 bp[2] End 34,971,713 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ventricular zone ganglionic eminence glutes monocyte caput epididymis gastric mucosa mucosa of ileum gastrocnemius muscle tibialis anterior muscle saphenous vein Top expressed in tail of embryo neural layer of retina genital tubercle granulocyte tibiofemoral joint ventricular zone renal corpuscle right ventricle thymus corneal stroma More reference expression data BioGPS More reference expression data
Gene ontology Molecular function oxidoreductase activity antioxidant activity dioxygenase activity metal ion binding histone demethylase activity transcription cis-regulatory region binding chromatin DNA binding histone H3-methyl-lysine-9 demethylase activity Cellular component chromatin nucleus nucleoplasm Biological process cellular oxidant detoxification response to cisplatin transcription, DNA-templated regulation of transcription, DNA-templated histone H3-K9 demethylation chromatin organization Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 51780 277250 Ensembl ENSG00000120733 ENSMUSG00000038773 UniProt Q7LBC6 Q6ZPY7 RefSeq (mRNA) NM_016604 NM_001081256 NM_029518 RefSeq (protein) NP_057688 NP_001074725 Location (UCSC) Chr 5: 138.35 – 138.44 Mb Chr 18: 34.91 – 34.97 Mb PubMed search [3] [4]
Wikidata
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