KDM7A

Lysine demethylase 7A is a protein that in humans is encoded by the KDM7A gene. ^[5]

KDM7A
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3KV5, 3KV6, 3KV9, 3KVA, 3KVB, 3U78
Identifiers
Aliases	KDM7A, JHDM1D, lysine demethylase 7A
External IDs	MGI: 2443388; HomoloGene: 25281; GeneCards: KDM7A; OMA:KDM7A - orthologs
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q34 Start 140,084,746 bp[1] End 140,176,983 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6|6 B1 Start 39,113,557 bp[2] End 39,183,723 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in cartilage tissue tendon of biceps brachii glutes bone marrow skin of thigh epithelium of nasopharynx monocyte buccal mucosa cell skin of hip bone marrow cells Top expressed in blood zygote granulocyte Rostral migratory stream vestibular sensory epithelium secondary oocyte left lung lobe mesenteric lymph nodes lobe of cerebellum cerebellar vermis More reference expression data BioGPS n/a
Gene ontology Molecular function 2-oxoglutarate-dependent dioxygenase activity iron ion binding histone H3-methyl-lysine-9 demethylase activity histone H4-methyl-lysine-20 demethylase activity dioxygenase activity metal ion binding methylated histone binding histone H3-methyl-lysine-36 demethylase activity oxidoreductase activity histone H3-tri/di-methyl-lysine-27 demethylase activity histone demethylase activity zinc ion binding Cellular component nucleoplasm nucleolus nucleus Biological process regulation of transcription, DNA-templated histone H3-K27 demethylation histone H3-K9 demethylation histone H4-K20 demethylation transcription, DNA-templated nervous system development positive regulation of transcription, DNA-templated histone H3-K36 demethylation midbrain development chromatin organization Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 80853 338523 Ensembl ENSG00000006459 ENSMUSG00000042599 UniProt Q6ZMT4 Q3UWM4 RefSeq (mRNA) NM_030647 NM_001033430 RefSeq (protein) NP_085150 NP_001028602 Location (UCSC) Chr 7: 140.08 – 140.18 Mb Chr 6: 39.11 – 39.18 Mb PubMed search [3] [4]
Wikidata
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