KHSRP

Far upstream element-binding protein 2 is a protein that in humans is encoded by the KHSRP gene.^[5][6][7]

KHSRP
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2HH2, 2HH3, 2JVZ, 2OPU, 2OPV, 4B8T
Identifiers
Aliases	KHSRP, FBP2, FUBP2, KSRP, KH-type splicing regulatory protein, p75
External IDs	OMIM: 603445; MGI: 1336214; HomoloGene: 2734; GeneCards: KHSRP; OMA:KHSRP - orthologs
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19p13.3 Start 6,413,102 bp[1] End 6,424,811 bp[1]
Gene location (Mouse) Chr. Chromosome 17 (mouse)[2] Band 17 D|17 29.63 cM Start 57,328,051 bp[2] End 57,338,522 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ventricular zone ganglionic eminence body of uterus right hemisphere of cerebellum left ovary right ovary canal of the cervix right testis right uterine tube left testis Top expressed in ventricular zone zygote tail of embryo hand neural layer of retina yolk sac genital tubercle secondary oocyte lip primary visual cortex More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA binding protein binding nucleic acid binding mRNA binding mRNA 3'-UTR AU-rich region binding RNA binding Cellular component cytoplasm cytosol membrane nucleoplasm cytoplasmic stress granule nucleus exosome (RNase complex) Biological process mRNA transport regulation of transcription, DNA-templated mRNA catabolic process RNA splicing, via transesterification reactions mRNA processing transcription, DNA-templated regulation of miRNA metabolic process RNA splicing cellular response to cytokine stimulus negative regulation of nitric oxide biosynthetic process positive regulation of mRNA catabolic process 3'-UTR-mediated mRNA destabilization regulation of mRNA stability miRNA metabolic process transport negative regulation of low-density lipoprotein particle clearance Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 8570 16549 Ensembl ENSG00000088247 ENSMUSG00000007670 UniProt Q92945 Q3U0V1 RefSeq (mRNA) NM_003685 NM_001366299 NM_001366300 NM_010613 RefSeq (protein) NP_003676 NP_001353228 NP_001353229 NP_034743 Location (UCSC) Chr 19: 6.41 – 6.42 Mb Chr 17: 57.33 – 57.34 Mb PubMed search [3] [4]
Wikidata
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