KIAA0999

KIAA0999 protein is a protein that in humans is encoded by the SIK3 gene.^[5][6][7] It is part of the salt-inducible kinase family.

SIK3
Identifiers
Aliases	SIK3, QSK, SIK-3, L19, KIAA0999, SIK family kinase 3, SEMDK
External IDs	OMIM: 614776; MGI: 2446296; HomoloGene: 57023; GeneCards: SIK3; OMA:SIK3 - orthologs
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q23.3 Start 116,843,402 bp[1] End 117,098,437 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 A5.2 Start 45,924,118 bp[2] End 46,135,492 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in external globus pallidus corpus callosum lateral nuclear group of thalamus pars reticulata sperm pars compacta inferior ganglion of vagus nerve ventral tegmental area middle frontal gyrus subthalamic nucleus Top expressed in substantia nigra lumbar subsegment of spinal cord medial geniculate nucleus medial dorsal nucleus lateral geniculate nucleus median eminence arcuate nucleus ciliary body nucleus accumbens inferior colliculi More reference expression data BioGPS More reference expression data
Gene ontology Molecular function transferase activity nucleotide binding protein kinase activity protein serine/threonine kinase activity protein binding ATP binding magnesium ion binding metal ion binding kinase activity tau-protein kinase activity Cellular component cytoplasm nucleoplasm Biological process protein phosphorylation phosphorylation microtubule cytoskeleton organization intracellular signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23387 70661 Ensembl ENSG00000160584 ENSMUSG00000034135 UniProt Q9Y2K2 Q6P4S6 RefSeq (mRNA) NM_001281748 NM_001281749 NM_025164 NM_001366686 NM_001366687 NM_027498 RefSeq (protein) NP_001268677 NP_001268678 NP_079440 NP_001353615 NP_001353616 NP_081774 Location (UCSC) Chr 11: 116.84 – 117.1 Mb Chr 9: 45.92 – 46.14 Mb PubMed search [3] [4]
Wikidata
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