KIF21A

Kinesin-like protein KIF21A is a protein that in humans is encoded by the KIF21A gene.^[5][6]

KIF21A
Identifiers
Aliases	KIF21A, CFEOM1, FEOM1, FEOM3A, kinesin family member 21A
External IDs	OMIM: 608283; MGI: 109188; HomoloGene: 56761; GeneCards: KIF21A; OMA:KIF21A - orthologs
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12q12 Start 39,293,228 bp[1] End 39,443,390 bp[1]
Gene location (Mouse) Chr. Chromosome 15 (mouse)[2] Band 15 E3|15 45.86 cM Start 90,817,479 bp[2] End 90,934,151 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in spinal ganglia pars compacta pons superior vestibular nucleus lateral nuclear group of thalamus pars reticulata bronchial epithelial cell palpebral conjunctiva Brodmann area 23 ventral tegmental area Top expressed in habenula facial motor nucleus ventricular zone dorsomedial hypothalamic nucleus primary motor cortex mammillary body ventromedial nucleus medial vestibular nucleus central gray substance of midbrain lateral hypothalamus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function microtubule binding microtubule motor activity nucleotide binding ATPase activity protein binding ATP binding Cellular component cytoplasm microtubule cytoskeleton kinesin complex cytosol plasma membrane Biological process microtubule-based movement Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55605 16564 Ensembl ENSG00000139116 ENSMUSG00000022629 UniProt Q7Z4S6 Q9QXL2 RefSeq (mRNA) NM_001173463 NM_001173464 NM_001173465 NM_017641 NM_001378439 NM_001378440 NM_001378441 NM_001109040 NM_001109041 NM_001109042 NM_016705 NM_001358050 RefSeq (protein) NP_001166934 NP_001166935 NP_001166936 NP_060111 NP_001365368 NP_001365369 NP_001365370 NP_001102510 NP_001102511 NP_001102512 NP_057914 NP_001344979 Location (UCSC) Chr 12: 39.29 – 39.44 Mb Chr 15: 90.82 – 90.93 Mb PubMed search [3] [4]
Wikidata
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KIF21A belongs to a family of plus end-directed kinesin motor proteins. Neurons use kinesin and dynein microtubule-dependent motor proteins to transport essential cellular components along axonal and dendritic microtubules.^[6]