KLF7

Kruppel-like factor 7 (ubiquitous), also known as KLF7, is a protein which in humans is encoded by the KLF7 gene.^[5][6]

KLF7
Identifiers
Aliases	KLF7, UKLF, Kruppel-like factor 7 (ubiquitous), Kruppel like factor 7
External IDs	OMIM: 604865; MGI: 1935151; HomoloGene: 2751; GeneCards: KLF7; OMA:KLF7 - orthologs
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2q33.3 Start 207,074,137 bp[1] End 207,167,267 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1|1 C2 Start 64,068,606 bp[2] End 64,161,441 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in buccal mucosa cell saphenous vein ganglionic eminence Achilles tendon spinal ganglia bone marrow cell sural nerve gonad hair follicle testicle Top expressed in Rostral migratory stream trigeminal ganglion spinal ganglia supraoptic nucleus lumbar spinal ganglion aortic valve ascending aorta barrel cortex saccule motor neuron More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA-binding transcription factor activity DNA binding transcription coactivator activity zinc ion binding metal ion binding nucleic acid binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component nucleus Biological process regulation of transcription by RNA polymerase II positive regulation of transcription, DNA-templated regulation of transcription, DNA-templated axonogenesis transcription, DNA-templated dendrite morphogenesis axon guidance transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of epidermal cell differentiation regulation of insulin secretion negative regulation of adipose tissue development negative regulation of transcription by RNA polymerase II glucose homeostasis negative regulation of insulin secretion involved in cellular response to glucose stimulus Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 8609 93691 Ensembl ENSG00000118263 ENSMUSG00000025959 UniProt O75840 Q99JB0 RefSeq (mRNA) NM_001270942 NM_001270943 NM_001270944 NM_003709 NM_033563 RefSeq (protein) NP_001257871 NP_001257872 NP_001257873 NP_003700 NP_291041 Location (UCSC) Chr 2: 207.07 – 207.17 Mb Chr 1: 64.07 – 64.16 Mb PubMed search [3] [4]
Wikidata
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This protein is a member of the Kruppel-like family of transcription factors.^[7]