KRT23

Keratin, type I cytoskeletal 23 is a protein that in humans is encoded by the KRT23 gene.^[5][6][7]

KRT23
Identifiers
Aliases	KRT23, CK23, HAIK1, K23, keratin 23
External IDs	OMIM: 606194; MGI: 2148866; HomoloGene: 9172; GeneCards: KRT23; OMA:KRT23 - orthologs
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17q21.2 Start 40,922,700 bp[1] End 40,937,646 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11|11 D Start 99,368,800 bp[2] End 99,383,963 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in placenta skin of leg skin of abdomen olfactory zone of nasal mucosa salivary gland minor salivary glands blood islet of Langerhans tonsil right uterine tube Top expressed in otic placode esophagus epithelium of stomach lip submandibular gland skin of back saccule parotid gland mucous cell of stomach otic vesicle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function structural molecule activity Cellular component intermediate filament cytosol Biological process keratinization cornification Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 25984 94179 Ensembl ENSG00000108244 ENSG00000263309 ENSMUSG00000006777 UniProt Q9C075 Q99PS0 RefSeq (mRNA) NM_001282433 NM_015515 NM_173213 NM_033373 RefSeq (protein) NP_001269362 NP_056330 NP_203537 Location (UCSC) Chr 17: 40.92 – 40.94 Mb Chr 11: 99.37 – 99.38 Mb PubMed search [3] [4]
Wikidata
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The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratin and hair keratin. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21.^[7]