KRT31

Keratin, type I cuticular Ha1 is a protein that in humans is encoded by the KRT31 gene.^[5][6][7]

KRT31
Identifiers
Aliases	KRT31, HA1, Ha-1, KRTHA1, hHa1, keratin 31
External IDs	OMIM: 601077; MGI: 1309991; HomoloGene: 74433; GeneCards: KRT31; OMA:KRT31 - orthologs
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17q21.2 Start 41,393,721 bp[1] End 41,397,608 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11 D|11 63.37 cM Start 99,914,460 bp[2] End 99,920,694 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in cerebellum cerebellar cortex cerebellar hemisphere right hemisphere of cerebellum skin of abdomen testicle skin of leg muscle of thigh mucosa of esophagus anterior cingulate cortex Top expressed in lip hair filiform papilla outer root sheath of hair follicle ankle joint embryo cortex of hair skin of back skin of abdomen dermis More reference expression data BioGPS More reference expression data
Gene ontology Molecular function structural constituent of cytoskeleton protein binding structural molecule activity Cellular component extracellular exosome intermediate filament extracellular space cytosol Biological process epidermis development cytoskeleton organization keratinization cornification Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 3881 16671 Ensembl ENSG00000094796 ENSG00000262993 ENSMUSG00000057723 UniProt Q15323 Q61897 RefSeq (mRNA) NM_002277 NM_013570 RefSeq (protein) NP_002268 NP_038598 Location (UCSC) Chr 17: 41.39 – 41.4 Mb Chr 11: 99.91 – 99.92 Mb PubMed search [3] [4]
Wikidata
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Function

The protein encoded by this gene is a member of the keratin gene family. As a Type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q21.2 and have the same direction of transcription.^[7]