KRT33B

Keratin, type I cuticular Ha3-II is a protein that in humans is encoded by the KRT33B gene.^[5][6][7]

KRT33B
Identifiers
Aliases	KRT33B, HA3II, Ha-3II, K33B, KRTHA3A, KRTHA3B, hHa3-II, keratin 33B
External IDs	OMIM: 602762; MGI: 1919138; HomoloGene: 136754; GeneCards: KRT33B; OMA:KRT33B - orthologs
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17q21.2 Start 41,363,498 bp[1] End 41,369,813 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11|11 D Start 99,902,021 bp[2] End 99,907,038 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in prefrontal cortex anterior cingulate cortex skin of abdomen skin of leg Brodmann area 9 right lung mucosa of esophagus right frontal lobe vagina hippocampus proper Top expressed in lip hair follicle skin of back dermis skin of external ear skin of abdomen sexually immature organism medial head of gastrocnemius muscle conjunctival fornix diencephalon More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding structural molecule activity Cellular component extracellular exosome intermediate filament extracellular space cytosol Biological process hair cycle ageing keratinization cornification Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 3884 71888 Ensembl ENSG00000263012 ENSG00000131738 ENSMUSG00000035592 UniProt Q14525 Q8K0Y2 RefSeq (mRNA) NM_002279 NM_027983 RefSeq (protein) NP_002270 NP_082259 Location (UCSC) Chr 17: 41.36 – 41.37 Mb Chr 11: 99.9 – 99.91 Mb PubMed search [3] [4]
Wikidata
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The protein encoded by this gene is a member of the keratin gene family. It is one of the type I hair keratin genes which are clustered in a region of chromosome 17q21.2 and have the same direction of transcription. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II hair keratin to form hair and nails. There are two isoforms of this protein, encoded by two separate genes, KRT33A and KRT33B (this gene).^[7]