KRT36

Keratin, type I cuticular Ha6 is a protein that in humans is encoded by the KRT36 gene.^[5][6][7]

KRT36
Identifiers
Aliases	KRT36, HA6, KRTHA6, hHa6, keratin 36
External IDs	OMIM: 604540; MGI: 109364; HomoloGene: 88459; GeneCards: KRT36; OMA:KRT36 - orthologs
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17q21.2 Start 41,486,136 bp[1] End 41,492,546 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11|11 D Start 99,992,833 bp[2] End 99,996,452 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle body of tongue superior surface of tongue mucosa of esophagus spleen cervix lymph node skin of limb skin of leg granulocyte Top expressed in lip hair follicle embryo skin of external ear skin of back tongue filiform papilla skin of abdomen mammary gland oocyte More reference expression data BioGPS More reference expression data
Gene ontology Molecular function structural molecule activity structural constituent of skin epidermis Cellular component intermediate filament cytoskeleton extracellular exosome intermediate filament cytosol Biological process regulation of keratinocyte differentiation keratinization cornification biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 8689 16673 Ensembl ENSG00000126337 ENSMUSG00000020916 UniProt O76013 B1AQ75 RefSeq (mRNA) NM_003771 NM_001174099 NM_008472 RefSeq (protein) NP_003762 NP_001167570 Location (UCSC) Chr 17: 41.49 – 41.49 Mb Chr 11: 99.99 – 100 Mb PubMed search [3] [4]
Wikidata
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The protein encoded by this gene is a member of the keratin gene family. This type I hair keratin is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q21.2 and have the same direction of transcription.^[7]